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Recombinant Human GGCT Protein (His Tag)

Product Specifications

Background

Human Υ-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.

Abbreviation

GGCT

Synonyms

C7orf24; CRF21; Cytochrome C-Releasing Factor 21; GGCT; Gamma-Glutamylcyclotransferase

UniProt

O75223

Accession Number

O75223

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Leu188

Field of Research

Cell biology; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

23.2 kDa

Observed Molecular Weight

24-30 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Species

Human

Available Sizes

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