Recombinant Human Alpha-Parvin/PARVA Protein (His Tag)
Product Specifications
Background
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
Abbreviation
Alpha-Parvin; PARVA
Synonyms
Actopaxin; Alpha-Parvin; CH-ILKBP; Calponin-Like Integrin-Linked Kinase-Binding Protein; MXRA2; Matrix-Remodeling-Associated Protein 2; PARVA
UniProt
Q9NVD7
Accession Number
Q9NVD7
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Glu372
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 85 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
43.2 kDa
Observed Molecular Weight
50-62 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 40% Glycerol, pH 7.4.
Species
Human
Available Sizes
Documents
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