Recombinant Human ZWINT Protein (His Tag)
Product Specifications
Background
ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.
Abbreviation
ZWINT
Synonyms
ZW10 Interactor; ZW10-Interacting Protein 1; ZWINT; Zwint-1
UniProt
O95229
Accession Number
AAI10400.1
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Pro277
Field of Research
Cell biology; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/t9kzh8
Product MSDS
https://789.bio/eb/qz1qjP
Calculated Molecular Weight
33.4 kDa
Observed Molecular Weight
36 kDa
Species
Human
Available Sizes
Curated Selection
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