Recombinant Human XPNPEP3 Protein (His Tag)
Product Specifications
Background
Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.
Abbreviation
XPNPEP3
Synonyms
APP3; Aminopeptidase P3; Probable Xaa-Pro Aminopeptidase 3; X-Pro Aminopeptidase 3; XPNPEP3
UniProt
Q9NQH7
Accession Number
Q9NQH7
Expression System
E.coli
Tag
N-His & C-His
Sequence
Met 1-Ser507
Field of Research
Signal Transduction; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
60.2 kDa
Observed Molecular Weight
65 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 25mM Tris, 1mM DTT, pH 7.3.
Species
Human
Available Sizes
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