Recombinant Human VSTM1 Protein (His Tag)
Product Specifications
Background
V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17) . Inhibitory immune receptor involved in the regulation of phagocytes.
Abbreviation
VSTM1
Synonyms
SIRL-1; Signal inhibitory receptor on leukocytes-1; V-set and transmembrane domain-containing protein 1; VSTM1
UniProt
Q6UX27
Accession Number
Q6UX27
Expression System
HEK293 Cells
Tag
C-His
Sequence
Tyr17-Thr135
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
14.6 kDa
Observed Molecular Weight
25-35 kDa
Species
Human
Available Sizes
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