Recombinant Human Uroplakin-2/UPK2 Protein (His Tag)
Product Specifications
Background
Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER) . Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
Abbreviation
Uroplakin-2; UPK2
Synonyms
UP2; UPII; UPK2; Uroplakin II; Uroplakin-2
UniProt
O00526
Accession Number
O00526
Expression System
HEK293 Cells
Tag
C-His
Sequence
Asp26-Gly155
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://cdn.gentaur.com/products/763/68dd149a061270361e7ced97/datasheet/pksh033198.pdf
Product MSDS
https://789.bio/eb/qDKGOK
Calculated Molecular Weight
14.8 kDa
Observed Molecular Weight
27 kDa
Species
Human
Available Sizes
Curated Selection
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