Recombinant Human UBE2B/HR6B Protein
Product Specifications
Background
Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins; and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally; UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
Abbreviation
UBE2B; HR6B
Synonyms
HR6B; RAD6 Homolog B; RAD6B; UBE2B; Ubiquitin Carrier Protein B; Ubiquitin-Conjugating Enzyme E2 B; Ubiquitin-Conjugating Enzyme E2-17 kDa; Ubiquitin-Protein Ligase B; hHR6B
UniProt
P63146
Accession Number
P63146
Expression System
E.coli
Tag
None
Sequence
Met 1-Ser152
Field of Research
Cell biology; Cancer; epigenetics and nuclear signal; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
17.5 kDa
Observed Molecular Weight
18 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 10mM HEPES, pH 7.5.
Species
Human
Available Sizes
Curated Selection
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