Recombinant Human LSM1 Protein (His Tag)
Product Specifications
Background
U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.
Abbreviation
LSM1
Synonyms
CASM; Cancer-Associated Sm-Like; LSM1; Small Nuclear Ribonuclear CaSm; U6 snRNA-Associated Sm-Like Protein LSm1
UniProt
O15116
Accession Number
O15116
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Tyr133
Field of Research
Tags & Cell Markers; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
16.2 kDa
Observed Molecular Weight
19 kDa
Species
Human
Available Sizes
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