Recombinant Human INPP5A Protein (His Tag)
Product Specifications
Background
Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins (1,4,5) P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
Abbreviation
INPP5A
Synonyms
INPP5A; Type I inositol 1,4,5-trisphosphate 5-phosphatase
UniProt
Q14642
Accession Number
Q14642
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Val410
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
48.7 kDa
Observed Molecular Weight
45 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Species
Human
Available Sizes
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