Recombinant Human Tryptase β-2/TPSB2 Protein (His Tag)
Product Specifications
Background
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
Abbreviation
Tryptase β-2; TPSB2
Synonyms
TPS2; TPSB2; Tryptase Beta-2; Tryptase II; Tryptase-2
UniProt
P20231
Accession Number
AAH29356.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala19-Pro275
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
29.6 kDa
Observed Molecular Weight
30-35 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Species
Human
Available Sizes
Documents
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![HN1 Recombinant Rabbit Monoclonal Antibody [JE55-74]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea818a8/imageurl/ha721384.webp)
HA721384 100 µL
HN1 Recombinant Rabbit Monoclonal Antibody [JE55-74]
Sign In for Pricing
View Details 
