Recombinant Human TIMP-4/TIMP4 Protein (His Tag)
Product Specifications
Background
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Abbreviation
TIMP-4; TIMP4
Synonyms
Metalloproteinase inhibitor 4; TIMP-4; TIMP4; Tissue inhibitor of metalloproteinases 4
UniProt
Q99727
Accession Number
Q99727
Expression System
HEK293 Cells
Tag
C-His
Sequence
Cys30-Pro224
Field of Research
Cell biology; Cardiovascular; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
23.5 kDa
Observed Molecular Weight
24 kDa
Species
Human
Available Sizes
Documents
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