Recombinant Human Testin/TES Protein (His Tag)
Product Specifications
Background
Testin belongs to the prickle/espinas/testin family. Testin contains three LIM zinc-binding domains and one PET domain, TES as a scaffold protein that may have a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. In addition, TES can also as a tumor suppressor, inhibits tumor cell growth, regulate the cell proliferation.TES interacts with many cytoskeletal proteins, such as Zyxin, Mena, Actin, Talin and VASP. The ability of TES to associate with alpha-actin, Zyxin and paxillin is dependent on the conformational state of the molecule.
Abbreviation
Testin; TES
Synonyms
TES; TESS; Testin
UniProt
Q9UGI8
Accession Number
Q9UGI8
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Ser421
Field of Research
Signal Transduction; Cancer; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
49.1 kDa
Observed Molecular Weight
50 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, 1mM DTT, 10% Glycerol, pH 7.5.
Species
Human
Available Sizes
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