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Recombinant Human Tachykinin-3/TAC3 Protein (His Tag)

Product Specifications

Background

Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and contract many smooth muscles in pregnancy. TAC3 is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. It is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. TAC3 acts as the ligand for the neurokinin-3 receptor, mutations in this gene are associated with normosmic hypogonadotropic hypogonadism.

Abbreviation

Tachykinin-3; TAC3

Synonyms

NKB; NKNB; Neurokinin-B; Neuromedin-K; TAC3; Tachykinin-3; UNQ585/PRO1155; ZNEUROK1

UniProt

Q9UHF0

Accession Number

Q9UHF0

Expression System

E.coli

Tag

N-His

Sequence

Gln17-Glu121

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.9 kDa

Observed Molecular Weight

18 kDa

Species

Human

Available Sizes

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