Recombinant Human Tachykinin-3/TAC3 Protein (His Tag)
Product Specifications
Background
Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and contract many smooth muscles in pregnancy. TAC3 is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. It is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. TAC3 acts as the ligand for the neurokinin-3 receptor, mutations in this gene are associated with normosmic hypogonadotropic hypogonadism.
Abbreviation
Tachykinin-3; TAC3
Synonyms
NKB; NKNB; Neurokinin-B; Neuromedin-K; TAC3; Tachykinin-3; UNQ585/PRO1155; ZNEUROK1
UniProt
Q9UHF0
Accession Number
Q9UHF0
Expression System
E.coli
Tag
N-His
Sequence
Gln17-Glu121
Field of Research
Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
13.9 kDa
Observed Molecular Weight
18 kDa
Species
Human
Available Sizes
Curated Selection
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