Recombinant Human SPESP1 Protein (His Tag)
Product Specifications
Background
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may interact with IZUMO1 and MN9 antigen and it contains an N-glycosylation site as well as several cAMP-dependent kinase, protein kinase C, and casein kinase II consensus phosphorylation sites.
Abbreviation
SPESP1
Synonyms
ESP; Equatorial Segment Protein; Glycosylated 38 kDa Sperm Protein C-7/8; SP-ESP; SPESP1; Sperm Equatorial Segment Protein 1
UniProt
Q6UW49
Accession Number
Q6UW49
Expression System
HEK293 Cells
Tag
C-His
Sequence
Tyr20-Tyr350
Field of Research
Developmental Biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/ccds48
Product MSDS
https://789.bio/eb/brjHm9
Calculated Molecular Weight
37.9 kDa
Observed Molecular Weight
58 kDa
Species
Human
Available Sizes
Curated Selection
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