Recombinant Human SerpinH1/SERPINH1 Protein (His Tag)

Product Specifications

Background

Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.

Abbreviation

SerpinH1; SERPINH1

Synonyms

47 kDa Heat Shock Protein; Arsenic-Transactivated Protein 3; AsTP3; CBP1; CBP2; Cell Proliferation-Inducing Gene 14 Protein; Collagen-Binding Protein; Colligin; HSP47; Rheumatoid Arthritis-Related Antigen RA-A47; SERPINH1; SERPINH2; Serpin H1

UniProt

P50454

Accession Number

P50454

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala19-Leu418

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.