Recombinant Human SerpinA3/AACT Protein (His Tag)

Product Specifications

Background

Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease.

Abbreviation

SerpinA3; AACT

Synonyms

AACT; ACT; Alpha-1-Antichymotrypsin; Cell Growth-Inhibiting Gene 24/25 Protein; GIG24; GIG25; MGC88254; SERPINA3; Serpin A3

UniProt

P01011

Accession Number

P01011

Expression System

HEK293 Cells

Tag

C-His

Sequence

His24-Ala423 (Lys267Arg)

Field of Research

Cell biology; Cardiovascular; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.