Recombinant Human SENP8 Protein (His Tag)
Product Specifications
Background
Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
Abbreviation
SENP8
Synonyms
DEN1; Deneddylase-1; NEDD8-Specific Protease 1; NEDP1; PRSC2; Protease Cysteine 2; SENP8; Sentrin-Specific Protease 8; Sentrin/SUMO-Specific Protease SENP8
UniProt
Q96LD8
Accession Number
Q96LD8
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Lys212
Field of Research
Cell biology; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
26.2 kDa
Observed Molecular Weight
22 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Species
Human
Available Sizes
Documents
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