Recombinant Human Semenogelin-1/SEMG1 Protein (His Tag)

Product Specifications

Background

Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alpha-inhibin-92 and alpha-inhibin-31 are produced; they inhibit the secretion of pituitary follicle-stimulating hormone. At the same time, it breaks down the gel matrix, allowing the spermatozoa to move more freely.

Abbreviation

Semenogelin-1; SEMG1

Synonyms

Alpha-Inhibin-31; Alpha-Inhibin-92; SEMG; SEMG1; SGI; Semenogelin I; Semenogelin-1; Seminal Basic Protein

UniProt

P04279

Accession Number

AAH07096.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln24-Thr402

Field of Research

Cell biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.