Recombinant Human Semaphorin 3C/SEMA3C Protein (His Tag)
Product Specifications
Background
Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N-terminal Sema domain, a cysteine knot, a furine-type cleavage site, an Ig-like domain, and a C-terminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary and prostate, expressed lowly in the other organs, including the brain.
Abbreviation
Semaphorin 3C; SEMA3C
Synonyms
SEMA3C; SEMAE; Sema E; Semaphorin-3C; Semaphorin-E
UniProt
Q99985
Accession Number
Q99985
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gly21-Ser738
Field of Research
Cardiovascular; Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
82.4 kDa
Observed Molecular Weight
75-120&27KD
Formulation
24
Species
Human
Available Sizes
Documents
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