Recombinant Human S100P/S100E Protein (His Tag)
Product Specifications
Background
Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100P is 95 amino acids in length and it contains 2 EF-Hand Calcium-Binding Motifs. The EF-Hand Motif binds calcium; which likely alters molecular conformation. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and it is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. In addition to binding Ca; S100P also binds Zn and Mg; and may play a role in the etiology of prostate cancer.
Abbreviation
S100P; S100E
Synonyms
MIG9; Protein S100-E; Protein S100-P; S100 Calcium-Binding Protein P; S100E; S100P
UniProt
P25815
Accession Number
P25815
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Lys95
Field of Research
Signal Transduction; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
12.6 kDa
Observed Molecular Weight
12 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 100mM Nacl, 20% Glycerol, pH 8.0.
Species
Human
Available Sizes
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