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Recombinant Human S100P/S100E Protein (His Tag)

Product Specifications

Background

Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100P is 95 amino acids in length and it contains 2 EF-Hand Calcium-Binding Motifs. The EF-Hand Motif binds calcium; which likely alters molecular conformation. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and it is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. In addition to binding Ca; S100P also binds Zn and Mg; and may play a role in the etiology of prostate cancer.

Abbreviation

S100P; S100E

Synonyms

MIG9; Protein S100-E; Protein S100-P; S100 Calcium-Binding Protein P; S100E; S100P

UniProt

P25815

Accession Number

P25815

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Lys95

Field of Research

Signal Transduction; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

12.6 kDa

Observed Molecular Weight

12 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 100mM Nacl, 20% Glycerol, pH 8.0.

Species

Human

Available Sizes

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