Recombinant Human S100A8 Protein (His Tag)
Product Specifications
Background
Protein S100-A8 (also MRP8 and calgranulin A) is a calcium- and zinc-binding protein.It plays a prominent role in the regulation of inflammatory processes and immune response. S100A8 can induce neutrophil chemotaxis and adhesion. Its role as an oxidant scavenger has a protective role in preventing exaggerated tissue damage by scavenging oxidants. It can act as a potent amplifier of inflammation in autoimmunity as well as in cancer development and tumor spread.
Abbreviation
S100A8
Synonyms
60B8AG; CAGA; CFAG; CGLA; CP-10; Calgranulin-A; Cystic fibrosis antigen; L1Ag; Leukocyte L1 complex light chain; MA387; MIF; MRP-8; MRP8; NIF; P8; Protein S100-A8; S100A8
UniProt
P05109
Accession Number
P05109
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Glu93
Field of Research
Cell biology; Neuroscience; Cancer; epigenetics and nuclear signal; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
11.7 kDa
Observed Molecular Weight
13 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 150mM NaCl, 20% Glycerol, 2mM EDTA, 0.05% Tween 80, pH8.5
Species
Human
Available Sizes
Documents
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