Recombinant Human Proteoglycan 3/PRG3 Protein (His Tag)
Product Specifications
Background
Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils.
Abbreviation
Proteoglycan 3; PRG3
Synonyms
Eosinophil Major Basic Protein Homolog; MBPH; PRG3; Prepro-MBPH; Prepro-Major Basic Protein Homolog; Proteoglycan 3
UniProt
Q9Y2Y8
Accession Number
AAI13412.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Leu18-Phe225
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
24.6 kDa
Observed Molecular Weight
27 kDa
Species
Human
Available Sizes
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