Recombinant Human PPM1G/PP2C-gamma Protein (His Tag)
Product Specifications
Background
Protein Phosphatase 1G (PP1MG) is a cytoplasmic protein that belongs to the PP2C family. PPM1G is widely expressed; it is abundant in testis; skeletal muscle; and heart. PPM1G is a negative regulator of cell stress response pathways. PPM1G is responsible for the dephosphorylation of Pre-mRNA splicing factors; an important factor for the formation of functional spliceosome. PPM1G also plays a role in regulating cell cycle progression.
Abbreviation
PPM1G; PP2C-gamma
Synonyms
PP2C-Gamma; PP2CG; PP2CGAMMA; PPM1G; Protein Phosphatase 1C; Protein Phosphatase 1G; Protein Phosphatase 2C Isoform Gamma; Protein Phosphatase Magnesium-Dependent 1 Gamma
UniProt
O15355
Accession Number
O15355
Expression System
E.coli
Tag
C-His
Sequence
Met317-Asp546
Field of Research
Signal Transduction; Cell biology; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
26.2 kDa
Observed Molecular Weight
30 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 1mM DTT, 1mM EDTA, 2mM β-ME, 20% Glycerol, pH 7.5.
Species
Human
Available Sizes
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