Recombinant Human Progonadoliberin-2/GNRH2 Protein (His Tag)
Product Specifications
Background
Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold) . GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, but produce the same peptide hormone.
Abbreviation
Progonadoliberin-2; GNRH2
Synonyms
GNRH2; GnRH II; GnRH-Associated Peptide 2; GnRH-Associated Peptide II; Gonadoliberin II; Gonadoliberin-2; Gonadotropin-Releasing Hormone II; LH-RH II; Luliberin II; Luteinizing Hormone-Releasing Hormone II; Progonadoliberin II; Progonadoliberin-2
UniProt
O43555
Accession Number
O43555
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln24-Val120
Field of Research
Signal Transduction; Developmental Biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
11.6 kDa
Observed Molecular Weight
14-25 kDa
Species
Human
Available Sizes
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