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Recombinant Human PSG2 Protein (His Tag)

Product Specifications

Background

PSG2 is a secreted protein that in humans is encoded by the PSG2 gene. It is a member of the human pregnancy-specific glycoproteins (PSGs) family. These proteins are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. PSG2 consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. It has an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain.

Abbreviation

PSG2

Synonyms

PSBG2; PSG2; Pregnancy specific beta-1-glycoprotein 2; Pregnancy-specific beta-1 glycoprotein E; pregnancy-specific beta-1-glycoprotein 2; pregnancy-specific beta-1-glycoprotein 7

UniProt

P11465

Accession Number

P11465

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln35-Thr335

Field of Research

Tags & Cell Markers; Developmental Biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

34.5 kDa

Observed Molecular Weight

43 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Species

Human

Available Sizes

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