Recombinant Human POMGNT1 Protein (His Tag)
Product Specifications
Background
Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3) .
Abbreviation
POMGNT1
Synonyms
2-N-Acetylglucosaminyltransferase 1;2-N-Acetylglucosaminyltransferase I.2; MGAT1.2; POMGNT1; POMGnT1; Protein O-Linked-Mannose Beta-1; UDP-GlcNAc:Alpha-D-Mannoside Beta-1
UniProt
Q8WZA1
Accession Number
Q8WZA1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Leu59-Thr660
Field of Research
Tags & Cell Markers
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/diuipc
Product MSDS
https://789.bio/eb/m1mDO8
Calculated Molecular Weight
69.3 kDa
Observed Molecular Weight
74 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5.
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Anti-Flavivirus group antigen [D1-4G2-4-15 (4G2)], Goat IgG, kappa](https://cdn.genprice.uk/genprice/genprice5.png)
MBS489239-01 0.1 mg
Anti-Flavivirus group antigen [D1-4G2-4-15 (4G2)], Goat IgG, kappa
Ask
View Details MBS489239-02 5x 0.1 mg
Anti-Flavivirus group antigen [D1-4G2-4-15 (4G2)], Goat IgG, kappa
Ask
View Details MBS7230222-01 48 Well
Mouse Conserved oligomeric Golgi complex subunit 8 (COG8) ELISA Kit
Ask
View Details MBS7230222-02 96 Well
Mouse Conserved oligomeric Golgi complex subunit 8 (COG8) ELISA Kit
Ask
View Details