Recombinant Human Placental Lactogen/CSH1 Protein (His Tag)

Product Specifications

Background

Chorionic Somatomammotropin Hormone (CSH1) belongs to the Somatotropin/Prolactin family. It is located at the growth hormone locus on chromosome 17. It is produced by cells in the syncytiotrophoblast layer of the placenta only during pregnancy. Although CSH1 does not interact with GHR but only activates PRLR through zinc-induced dimerization. It is expressed mainly in the placenta and utilizes multiple transcription initiation sites. CSH1 plays an important role in stimulating lactation, growth control and metabolism.

Abbreviation

CSH1

Synonyms

CS-1; CSA; CSH1; CSH2; CSMT; Choriomammotropin; Chorionic Somatomammotropin Hormone; Lactogen; PL; Placental Lactogen; hCS-1; hCS-A

UniProt

P0DML2

Accession Number

P0DML2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Val27-Phe217

Field of Research

Signal Transduction; Developmental Biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.