Recombinant Human PGK1/PGKA Protein (His Tag)
Product Specifications
Background
Phosphoglycerate kinase 1 (PGK1) is an enzyme. It is mainly expressed in spermatogonia and Localized on the principle piece in the sperm. Its expression significantly decreased in the testis of elderly men. PGK1 involved in a critical energy-producing process known as glycolysis. It helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 may also act as a cofactor for polymerase alpha. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.
Abbreviation
PGK1; PGKA
Synonyms
Cell migration-inducing gene 10 protein; PGK1; PGKA; Phosphoglycerate kinase 1; Primer recognition protein 2
UniProt
P00558
Accession Number
P00558
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ser2-Ile417
Field of Research
Signal Transduction; Cardiovascular; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
45.5 kDa
Observed Molecular Weight
37-50 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0.
Species
Human
Available Sizes
Documents
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