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Recombinant Human PITPNA Protein (His Tag)

Product Specifications

Background

Phosphatidylinositol Transfer Protein α Isoform (PITPNA) is found in the cytoplasm and belongs to the PtdIns transfer protein family. PITPNA is a ubiquitous and highly conserved protein in multicellular eukaryotes that catalyzes the exchange of phospholipids between membranes and participates in cellular phospholipid metabolism, signal transduction and vesicular trafficking in vivo. It is expressed in a wide range of tissues and implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.

Abbreviation

PITPNA

Synonyms

PI-TP-Alpha; PITPN; PITPNA; Phosphatidylinositol Transfer Protein Alpha Isoform; PtdIns Transfer Protein Alpha; PtdInsTP Alpha

UniProt

Q00169

Accession Number

Q00169

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Asp270

Field of Research

Signal Transduction; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

34.0 kDa

Observed Molecular Weight

16&22&38 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM EDTA, 1mM DTT, pH 8.0.

Species

Human

Available Sizes

Frequently Asked Questions

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