Recombinant Human PITPNA Protein (His Tag)
Product Specifications
Background
Phosphatidylinositol Transfer Protein α Isoform (PITPNA) is found in the cytoplasm and belongs to the PtdIns transfer protein family. PITPNA is a ubiquitous and highly conserved protein in multicellular eukaryotes that catalyzes the exchange of phospholipids between membranes and participates in cellular phospholipid metabolism, signal transduction and vesicular trafficking in vivo. It is expressed in a wide range of tissues and implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.
Abbreviation
PITPNA
Synonyms
PI-TP-Alpha; PITPN; PITPNA; Phosphatidylinositol Transfer Protein Alpha Isoform; PtdIns Transfer Protein Alpha; PtdInsTP Alpha
UniProt
Q00169
Accession Number
Q00169
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Asp270
Field of Research
Signal Transduction; Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
34.0 kDa
Observed Molecular Weight
16&22&38 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM EDTA, 1mM DTT, pH 8.0.
Species
Human
Available Sizes
Documents
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