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Recombinant Human PPIase/FKBP7 Protein (aa 24-222, His Tag)

Product Specifications

Background

Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 (FKBP7) is a member of the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. FKBP7 exhibits PPIase activity and function as molecular chaperones. In addition, FKBP7 accelerates the folding of proteins during protein synthesis. It has been shown that Hsp90 complex to the nucleus bind its PPIase domain to cytoplasmic dynein, the motor protein responsible for retrograde movement along microtubules.

Abbreviation

PPIase; FKBP7

Synonyms

23 kDa FK506-Binding Protein;23 kDa FKBP; FK506-Binding Protein 7; FKBP-23; FKBP-7; FKBP23; FKBP7; PPIase FKBP7; Peptidyl-Prolyl Cis-Trans Isomerase FKBP7; Rotamase

UniProt

Q9Y680

Accession Number

Q9Y680

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln24-Leu222

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

23.9 kDa

Observed Molecular Weight

25-32 kDa

Formulation

2

Species

Human

Available Sizes

Frequently Asked Questions

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