Recombinant Human PPIase/FKBP7 Protein (aa 24-222, His Tag)
Product Specifications
Background
Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 (FKBP7) is a member of the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. FKBP7 exhibits PPIase activity and function as molecular chaperones. In addition, FKBP7 accelerates the folding of proteins during protein synthesis. It has been shown that Hsp90 complex to the nucleus bind its PPIase domain to cytoplasmic dynein, the motor protein responsible for retrograde movement along microtubules.
Abbreviation
PPIase; FKBP7
Synonyms
23 kDa FK506-Binding Protein;23 kDa FKBP; FK506-Binding Protein 7; FKBP-23; FKBP-7; FKBP23; FKBP7; PPIase FKBP7; Peptidyl-Prolyl Cis-Trans Isomerase FKBP7; Rotamase
UniProt
Q9Y680
Accession Number
Q9Y680
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln24-Leu222
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
23.9 kDa
Observed Molecular Weight
25-32 kDa
Formulation
2
Species
Human
Available Sizes
Curated Selection
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