Recombinant Human FKBP2 Protein (His Tag)
Product Specifications
Background
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds.
Abbreviation
FKBP2
Synonyms
FK506-binding protein 2; Immunophilin FKBP13; Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2 for short) ; Rotamase; also named 13 kDa FK506-binding protein
UniProt
P26885
Accession Number
P26885
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala22-Leu142
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
14.3 kDa
Observed Molecular Weight
17 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mm NaCl, pH 7.5.
Species
Human
Available Sizes
Documents
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