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Recombinant Human Cyclophilin D/PPID Protein (His Tag)

Product Specifications

Background

Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.

Abbreviation

Cyclophilin D; PPID

Synonyms

40 kDa Peptidyl-Prolyl Cis-Trans Isomerase; CYP-40; CYP40; CYPD; Cyclophilin-40; Cyclophilin-Related Protein; PPID; PPIase D; Peptidyl-Prolyl Cis-Trans Isomerase D; Rotamase D

UniProt

Q08752

Accession Number

Q08752

Expression System

E.coli

Tag

N-His & C-His

Sequence

Met 1-Ala370

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

43.9 kDa

Observed Molecular Weight

40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Species

Human

Available Sizes

Frequently Asked Questions

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