Recombinant Human Cyclophilin D/PPID Protein (His Tag)
Product Specifications
Background
Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.
Abbreviation
Cyclophilin D; PPID
Synonyms
40 kDa Peptidyl-Prolyl Cis-Trans Isomerase; CYP-40; CYP40; CYPD; Cyclophilin-40; Cyclophilin-Related Protein; PPID; PPIase D; Peptidyl-Prolyl Cis-Trans Isomerase D; Rotamase D
UniProt
Q08752
Accession Number
Q08752
Expression System
E.coli
Tag
N-His & C-His
Sequence
Met 1-Ala370
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
43.9 kDa
Observed Molecular Weight
40 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
Species
Human
Available Sizes
Documents
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