Recombinant Human Peptidase D/PEPD Protein
Product Specifications
Background
PEPD belongs to the peptidase M24B family of Eukaryotic-type prolidase subfamily. PEPD is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus. It is important in collagen metabolism because of the high levels of imino acids. Defects in PEPD are a cause of prolidase deficiency which is an autosomal recessive disorder associated with iminodipeptiduria.
Abbreviation
Peptidase D; PEPD
Synonyms
Imidodipeptidase; PEPD.; PRD; PeptidaseD; Prolinedipeptidase; Xaa-Pro dipeptidase
UniProt
P12955
Accession Number
AAH28295.1
Expression System
E.coli
Tag
None
Sequence
Ala2-Lys493
Field of Research
Signal Transduction; Cell biology; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
54.5 kDa
Observed Molecular Weight
60 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 25 mM Tris-HCl, 100 mM Glycine, 10% Glycerol, pH 8.5.
Species
Human
Available Sizes
Documents
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