Recombinant Human PDCD10/TFAR15 Protein
Product Specifications
Background
Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is required for normal cardiovascular development and normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Defects in PDCD10 are the cause of cerebral cavernous malformations type 3.
Abbreviation
PDCD10; TFAR15
Synonyms
CCM3; Cerebral Cavernous Malformations 3 Protein; PDCD10; Programmed Cell Death Protein 10; TF-1 Cell Apoptosis-Related Protein 15; TFAR15
UniProt
Q9BUL8
Accession Number
Q9BUL8
Expression System
E.coli
Tag
None
Sequence
Met 1-Ala212
Field of Research
Signal Transduction; Cell biology; Neuroscience; Developmental Biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
24.9 kDa
Observed Molecular Weight
28 kDa
Species
Human
Available Sizes
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