Recombinant Human PDCD10/TFAR15 Protein

Product Specifications

Background

Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is required for normal cardiovascular development and normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Defects in PDCD10 are the cause of cerebral cavernous malformations type 3.

Abbreviation

PDCD10; TFAR15

Synonyms

CCM3; Cerebral Cavernous Malformations 3 Protein; PDCD10; Programmed Cell Death Protein 10; TF-1 Cell Apoptosis-Related Protein 15; TFAR15

UniProt

Q9BUL8

Accession Number

Q9BUL8

Expression System

E.coli

Tag

None

Sequence

Met 1-Ala212

Field of Research

Signal Transduction; Cell biology; Neuroscience; Developmental Biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.