Recombinant Human PPT1 Protein (His Tag)
Product Specifications
Background
Palmitoyl-protein thioesterase 1 (PPT-1 for short), also known as Palmitoyl-protein hydrolase 1, belongs to the palmitoyl-protein thioesterase family. It is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. This enzyme removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Defects in PPT1 are the cause of neuronal ceroid lipofuscinosis type 1.
Abbreviation
PPT1
Synonyms
PPT-1; PPT1; Palmitoyl-protein hydrolase 1; Palmitoyl-protein thioesterase 1
UniProt
P50897
Accession Number
P50897
Expression System
HEK293 Cells
Tag
C-His
Sequence
Asp28-Gly306
Field of Research
Signal Transduction; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
32.3 kDa
Observed Molecular Weight
34-41 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Species
Human
Available Sizes
Curated Selection
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