Recombinant Human NFYA Protein

Product Specifications

Background

Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor ; which is composed of three components; NF-YA; NF-YB and NF-YC; binds to CCAAT motifs in the promoter regions in a variety of genes. NFYA forms a highly conserved transcription factor which stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters; for example in type 1 collagen; albumin and beta-actin genes.

Abbreviation

NFYA

Synonyms

CAAT Box DNA-Binding Protein Subunit A; NF-YA; NFYA; Nuclear Transcription Factor Y Subunit A; Nuclear Transcription Factor Y Subunit Alpha

UniProt

P23511

Accession Number

P23511-2

Expression System

E.coli

Tag

None

Sequence

Met 1-Ser318

Field of Research

Epigenetics and Nuclear Signaling

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.