Recombinant Human SGSH Protein (His Tag)
Product Specifications
Background
N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
Abbreviation
SGSH
Synonyms
HSS; N-Sulphoglucosamine Sulphohydrolase; SGSH; Sulfoglucosamine Sulfamidase; Sulphamidase
UniProt
P51688
Accession Number
P51688
Expression System
HEK293 Cells
Tag
C-His
Sequence
Arg21-Leu502
Field of Research
Signal Transduction; Tags & Cell Markers; Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
55.7 kDa
Observed Molecular Weight
63 kDa
Formulation
2
Species
Human
Available Sizes
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