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Recombinant Human SGSH Protein (His Tag)

Product Specifications

Background

N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.

Abbreviation

SGSH

Synonyms

HSS; N-Sulphoglucosamine Sulphohydrolase; SGSH; Sulfoglucosamine Sulfamidase; Sulphamidase

UniProt

P51688

Accession Number

P51688

Expression System

HEK293 Cells

Tag

C-His

Sequence

Arg21-Leu502

Field of Research

Signal Transduction; Tags & Cell Markers; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

55.7 kDa

Observed Molecular Weight

63 kDa

Formulation

2

Species

Human

Available Sizes

Curated Selection

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