Recombinant Human NDRG1 Protein (His Tag)

Product Specifications

Background

Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the α/β Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression; overexpression of NDRG1 is connected to malignant status of esophageal cancer.

Abbreviation

NDRG1

Synonyms

CAP43; DRG-1; DRG1; Differentiation-Related Gene 1 Protein; N-myc Downstream-Regulated Gene 1 Protein; NDRG1; Nickel-Specific Induction Protein Cap43; Protein NDRG1; RTP; Reducing Agents and Tunicamycin-Responsive Protein; Rit42

UniProt

Q92597

Accession Number

Q92597

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Cys394

Field of Research

Signal Transduction; Neuroscience; Cancer; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.