Recombinant Human ULBP2/N2DL-2 Protein (Fc Tag)

Product Specifications

Background

NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D; an activating receptor expressed on NK cells; NKT cells; T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.

Abbreviation

ULBP2; N2DL-2

Synonyms

ALCAN-Alpha; N2DL-2; N2DL2; NKG2D Ligand 2; NKG2DL2; RAET1H; Retinoic Acid Early Transcript 1H; UL16-Binding Protein 2; ULBP2

UniProt

Q9BZM5

Accession Number

Q9BZM5

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gly26-Ser217

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.