Recombinant Human ULBP2/N2DL-2 Protein (His Tag)
Product Specifications
Background
NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D; an activating receptor expressed on NK cells; NKT cells; T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.
Abbreviation
ULBP2; N2DL-2
Synonyms
ALCAN-Alpha; N2DL-2; N2DL2; NKG2D Ligand 2; NKG2DL2; RAET1H; Retinoic Acid Early Transcript 1H; UL16-Binding Protein 2; ULBP2
UniProt
Q9BZM5
Accession Number
Q9BZM5
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gly26-Ser217
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/cx9vhr
Product MSDS
https://789.bio/eb/fvHuXP
Calculated Molecular Weight
22.8 kDa
Observed Molecular Weight
30 kDa
Species
Human
Available Sizes
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