Recombinant Human SNU13 Protein (His Tag)

Product Specifications

Background

NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 has been shown to interact with RAD17and PRPF31. The protein undergoes a conformational change upon RNA-binding. NHP2L1 binds to the 5-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly, prior to step I of splicing catalysis.

Abbreviation

SNU13

Synonyms

High Mobility Group-Like Nuclear Protein 2 Homolog 1; NHP2-Like Protein 1; NHP2L1; OTK27; SNU13 Homolog; U4/U6.U5 tri-snRNP 15.5 kDa Protein; hSNU13

UniProt

P55769

Accession Number

P55769

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Val128

Field of Research

Epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.