Recombinant Human Neuroplastin/NPTN Protein (His Tag)
Product Specifications
Background
Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.
Abbreviation
Neuroplastin; NPTN
Synonyms
NPTN; Neuroplastin; SDFR1; SDR-1; SDR1; Stromal Cell-Derived Receptor 1
UniProt
Q9Y639
Accession Number
Q9Y639
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln29-His220
Field of Research
Cancer; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/qilx9c
Product MSDS
https://789.bio/eb/nzrXzP
Calculated Molecular Weight
22.7 kDa
Observed Molecular Weight
35-55 kDa
Species
Human
Available Sizes
Curated Selection
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