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Recombinant Human ACY3 Protein (His Tag)

Product Specifications

Background

Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1 and ASPA2, is a member of the Aspartoacylase subfamily. ACY3 plays an important role in deacetylating mercapturic acids in kidney proximal tubules and acts on N-acetyl-aromatic amino acids.ACY3 is located in the cytoplasm of S2 and S3 proximal tubules and the apical domain of S1 proximal tubules. ACY3 protein is also expressed at low levels in stomach, testis, heart, brain, lung and liver, and may function as an HCV (Hepatitis C virus) core binding protein.

Abbreviation

ACY3

Synonyms

ACY-3; ACY3; ASPA2; Acylase III; Aminoacylase-3; Aspartoacylase-2; HCBP1; HCV core-binding protein 1; Hepatitis C virus core-binding protein 1; N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)

UniProt

Q96HD9

Accession Number

Q96HD9

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Ser319

Field of Research

Signal Transduction; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

37.4 kDa

Observed Molecular Weight

35 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0.

Species

Human

Available Sizes

Frequently Asked Questions

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