Recombinant Human ACY3 Protein (His Tag)
Product Specifications
Background
Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1 and ASPA2, is a member of the Aspartoacylase subfamily. ACY3 plays an important role in deacetylating mercapturic acids in kidney proximal tubules and acts on N-acetyl-aromatic amino acids.ACY3 is located in the cytoplasm of S2 and S3 proximal tubules and the apical domain of S1 proximal tubules. ACY3 protein is also expressed at low levels in stomach, testis, heart, brain, lung and liver, and may function as an HCV (Hepatitis C virus) core binding protein.
Abbreviation
ACY3
Synonyms
ACY-3; ACY3; ASPA2; Acylase III; Aminoacylase-3; Aspartoacylase-2; HCBP1; HCV core-binding protein 1; Hepatitis C virus core-binding protein 1; N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
UniProt
Q96HD9
Accession Number
Q96HD9
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Ser319
Field of Research
Signal Transduction; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
37.4 kDa
Observed Molecular Weight
35 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0.
Species
Human
Available Sizes
Curated Selection
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