Recombinant Human MPZL1 Protein (His Tag)

Myelin protein zero-like protein 1 (MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.

FLJ96614; Homo sapiens myelin protein zero-like 1 (MPZL1) ; Mrna; Myelin protein zero-like 1; cDNA; cDNA FLJ78597; highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1) ; isoform CRA_b; mRNA; transcript variant 1

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.